SNRNP200 antibody

SNRNP200 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

SNRNP200 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HEK-293 cells, Jurkat cells, NIH/3T3 cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 200-245 kDa

ELISA, WB, IP

Human, Mouse; other species not tested.

ASCC3L1 antibody; BRR2 antibody; BRR2 homolog antibody; HELIC2 antibody; KIAA0788 antibody; SNRNP200 antibody; U5 200KD antibody

Rabbit IgG

This antibody was obtained by immunization of SNRNP200 recombinant protein (Accession Number: BC001417). Purification method: Antigen Affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

SNRNP200 (small nuclear ribonucleoprotein 200kDa (U5)), also known as HELIC2, ASCC3L1 or BRR2, is a 2,136 amino acid protein that localizes to the nucleus and contains two SEC63 domains, two helicase C-terminal domains and two helicase ATP-binding domains. Existing as multiple alternatively spliced isoforms, HELIC2 functions as an RNA helicase that is thought to promote specific RNA-RNA conformational changes which are important in the second step of RNA splicing. The gene encoding HELIC2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, hich also map to chromosome 2. The observed molecular weight of SNRNP200 is 200-245kd.