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Product Name
SNCAIP antibody
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Description
SNCAIP Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue. Positive WB detected in mouse brain tissue, fetal human brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 100, 75 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
SNCAIP antibody; Sph1 antibody; Synphilin 1 antibody; SYPH1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SNCAIP recombinant protein (Accession Number: NM_001242935). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115450(SNCAIP Antibody) at dilution of 1:300
IP Result of anti-SNCAIP (IP:Catalog No:115450, 4ug; Detection:Catalog No:115450 1:300) with mouse brain tissue lysate 3600ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:115450(SNCAIP Antibody) at dilution of 1:50 (under 40x lens)
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Background
SNCAIP, also named as Synphilin-1 or Alpha-synuclein-interacting protein, is a 919 amino acid protein, which contains six ANK repeats. SNCAIP is detected in brain and is widely expressed, with highest levels in brain, heart and placenta. SNCAIP localizes in the cytoplasm and inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. SNCAIP has an association with Parkinson disease.
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