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Product Name
SMU1 Polyclonal Antibody
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Description
Polyclonal antibody to SMU1
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
SMU1 antibody; BWD antibody; SMU-1 antibody; fSAP57 antibody; WD40 repeat-containing protein SMU1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:2000
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Validations
Western blot - SMU1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SMU1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
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Background
Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).; (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"