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Product Name
SMARCD1 antibody
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Description
SMARCD1 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells, HepG2 cells, human brain tissue. Observed molecular weight by Western-blot: 58 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
BAF60A antibody; BRG1 assOCiated factor 60A antibody; CRACD1 antibody; Rsc6p antibody; SMARCD1 antibody; SWI/SNF complex 60 kDa subunit antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of SMARCD1 recombinant protein (Accession Number: BC009368). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107589(SMARCD1 antibody) at dilution of 1:1000
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Background
SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1), also known as BAF60a (BRG1-associated factor 60A),Rsc6p or CRACD1, is a 476 amino acid protein that localizes to the nucleus and contains one SWIB domain. Expressed ubiquitously with notable expression in liver, brain, muscle, lung, kidney, pancreas and placenta, SMARCD1 functions as a component of the BAF complex and, in conjunction with a variety of other proteins, plays an essential role in chromatin remodeling. In addition, SMARCD1 influences vitamin D-mediated transcriptional activity and is thought to provide a link between the vitamin D receptor (VDR) and SWI/SNF chromatin remodeling complexes. Multiple isoforms of BAF60a exist due to alternative splicing events.
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