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Product Name
SLC6A4 Polyclonal Antibody
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Description
Polyclonal antibody to SLC6A4
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Tested applications
WB
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Species reactivity
Mouse, Rat
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Alternative names
SLC6A4 antibody; 5-HTT antibody; 5-HTTLPR antibody; 5HTT antibody; HTT antibody; OCD1 antibody; SERT antibody; SERT1 antibody; hSERT antibody; solute carrier family 6 member 4 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human SLC6A4 (NP_001036.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - SLC6A4 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SLC6A4 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.
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Background
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"