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Product Name
SLC3A1 antibody
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Description
SLC3A1 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human small intestine tissue. Positive WB detected in HEK-293 cells, HeLa cells, mouse kidney tissue. Positive IP detected in mouse kidney tissue. Observed molecular weight by Western-blot: 85 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ATR1 antibody; CSNU1 antibody; D2H antibody; FLJ34681 antibody; NBAT antibody; RBAT antibody; SLC3A1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SLC3A1 recombinant protein (Accession Number: NM_000341). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:115376(SLC3A1 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human kidney using Catalog No:115376(SLC3A1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human kidney using Catalog No:115376(SLC3A1 antibody) at dilution of 1:100 (under 40x lens)
IP Result of anti-SLC3A1 (IP:Catalog No:115376, 4ug; Detection:Catalog No:115376 1:1000) with mouse kidney tissue lysate 4000ug.
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Background
SLC3A1(Neutral and basic amino acid transport protein rBAT) is also named as NBAT,D2h,RBAT. It is involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity).SLC3A1 can be degraded, at least in part, via the endoplasmic reticulum-associated degradation (ERAD) pathway(PMID:18332091).
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References
- Takasato M, Er PX, Becroft M. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nature cell biology. 16(1):118-26. 2014.
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