SLC30A8/ZNT8-Specific antibody

Cat.#: 115365

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Product Information

  • Product Name
    SLC30A8/ZNT8-Specific antibody
  • Documents
  • Description
    SLC30A8/ZNT8-Specific Rabbit Polyclonal antibody. Positive IHC detected in human pancreas tissue, human liver cancer tissue. Positive WB detected in mouse pancreas tissue. Observed molecular weight by Western-blot: 45-50 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    SLC30A8 antibody; Zinc transporter 8 antibody; ZnT 8 antibody; ZNT8 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_173851). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:500

    mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human pancreas using Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas using Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas using Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human pancreas using Catalog No:115365(SLC30A8-Specific antibody) at dilution of 1:50 (under 40x lens)

  • Background
    SLC30A8 (also named as ZNT8) encods the secretory granule zinc transporter, permiting cellular efflux of zinc. SLC30A8 was recently defined as a autoantigen candidates of type 2 diabetes, although the molecular mechanism through which this phenotype is manifest is incompletely understood.
  • References
    • Xu G, Kang D, Zhang C. Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression. Investigative ophthalmology & visual science. 56(13):8166-78. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"