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Product Name
SLC30A6 antibody
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Description
SLC30A6 Rabbit Polyclonal antibody. Positive WB detected in A375 cells, K-562 cells. Observed molecular weight by Western-blot: 51 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
FLJ31101 antibody; MST103 antibody; MSTP103 antibody; SLC30A6 antibody; Zinc transporter 6 antibody; ZnT 6 antibody; ZNT6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SLC30A6 recombinant protein (Accession Number: BC032525). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
A375 cells were subjected to SDS PAGE followed by western blot with Catalog No:115364(SLC30A6 antibody) at dilution of 1:500
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Background
SLC30A6 represents solute carrier family 30 (zinc transporter), member 6
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References
- Fukunaka A, Kurokawa Y, Teranishi F. Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway. The Journal of biological chemistry. 286(18):16363-73. 2011.
- Kanninen KM, Grubman A, Caragounis A. Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis. Biology open. 2(6):635-46. 2013.
- Grubman A, Lidgerwood GE, Duncan C. Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder. Acta neuropathologica communications. 2:25. 2014.
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- Kaneko M, Noguchi T, Ikegami S. Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis. Journal of neuroscience research. 93(2):370-9. 2015.
- Grubman A, Pollari E, Duncan C. Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses? Metallomics : integrated biometal science. 6(4):932-43. 2014.
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