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Product Name
SLC25A11 Polyclonal Antibody
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Description
Polyclonal antibody to SLC25A11
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
SLC25A11 antibody; OGC antibody; SLC20A4 antibody; solute carrier family 25 member 11 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-314 of human SLC25A11 (NP_003553.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100 -
Validations
Western blot - SLC25A11 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SLC25A11 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
Immunohistochemistry - SLC25A11 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat spleen using SLC25A11 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC25A11 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using SLC25A11 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC25A11 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using SLC25A11 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SLC25A11 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse spinal cord using SLC25A11 antibody at dilution of 1:100 (40x lens).
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Background
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity). Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"