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Product Name
SLC24A4 antibody
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Description
SLC24A4 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 62-90kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse; other species not tested.
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Alternative names
SLC24A4 antibody; SHEP6 antibody; SLC24A2 antibody; NCKX4 antibody; FLJ38852 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_153646). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115318(SLC24A4 antibody) at dilution of 1:300
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Background
SLC24A4, also named as NCKX4, belongs to the sodium/potassium/calcium exchanger family. SLC24A4 transports 1 Ca2+ and 1 K+ in exchange for 4 Na+. Genetic variations in SLC24A4 are associated with skin/hair/eye pigmentation type 6 (SHEP6).
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References
- Lacruz RS, Smith CE, Bringas P. Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling. Journal of cellular physiology. 227(5):2264-75. 2012.
- Hu P, Lacruz RS, Smith CE, Smith SM, Kurtz I, Paine ML. Expression of the sodium/calcium/potassium exchanger, NCKX4, in ameloblasts. Cells, tissues, organs. 196(6):501-9. 2012.
- Bronckers AL, Lyaruu D, Jalali R, Medina JF, Zandieh-Doulabi B, DenBesten PK. Ameloblast Modulation and Transport of Cl⁻, Na⁺, and K⁺ during Amelogenesis. Journal of dental research. 94(12):1740-7. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"