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Product Name
SLC16A2 antibody
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Description
SLC16A2 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, L02 cells, mouse kidney tissue. Observed molecular weight by Western-blot: 50-65kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AHDS antibody; DXS128 antibody; DXS128E antibody; MCT 7 antibody; MCT 8 antibody; MCT7 antibody; MCT8 antibody; MonOCarboxylate transporter 7 antibody; MonOCarboxylate transporter 8 antibody; MRX22 antibody; SLC16A2 antibody; XPCT antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_006517). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115305(SLC16A2 antibody) at dilution of 1:600
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Background
SLC16A2, also named as MCT8 and XPCT, belongs to the major facilitator superfamily and Monocarboxylate porter (TC 2.A.1.13) family. SLC16A2 is a very active and specific thyroid hormone transporter. SLC16A2 stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. It does not transport Leu, Phe, Trp or Tyr. Defects in SLC16A2 are the cause of monocarboxylate transporter 8 deficiency (MCT8 deficiency). This antibody is specific to SLC16A2.
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References
- Schutkowski A, Wege N, Stangl GI, König B. Tissue-specific expression of monocarboxylate transporters during fasting in mice. PloS one. 9(11):e112118. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"