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Product Name
SLC12A5-Specific antibody
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Description
SLC12A5-Specific Rabbit Polyclonal antibody. Positive IHC detected in human brain. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 126kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
SLC12A5 antibody; K Cl cotransporter 2 antibody; KCC2 antibody; Neuronal K Cl cotransporter antibody; hKCC2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_020708). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:115300(SLC12A5-Specific antibody) at dilution of 1:100 (under 40x lens)
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Background
SLC12A5, also named as KCC2 and KIAA1176, belongs to the SLC12A transporter family. SLC12A5 mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. SLC12A5 is important for Cl- homeostasis in neurons. The antibody is specific to SLC12A5.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"