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Product Name
Human SIGLEC6 / CD327 (Fc Tag) recombinant protein
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Description
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
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Protein name
Sialic acid-binding Ig-like lectin 6
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Protein short names
CD33L; CD33L2; CD33L1; OBBP1; SIALIC ACID BINDING IG-LIKE LECTIN 6; SIGLEC6; CD33 ANTIGEN-LIKE 1; CD327; CDW327; OBESITY-BINDING PROTEIN 1
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Uniprot ID
O43699
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Gene Name
SIGLEC6; CD33L; CD33L1; OBBP1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SIGLEC6 (O43699-3) (Gln27-Val331) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SIGLEC6/Fc is a disulfide-linked homodimer. The reduced monomer comprises 546 amino acids and has a predicted molecular mass of 60.7 kDa. The apparent molecular mass of the protein is approximately 66-73 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human SIGLEC6 / CD327 Protein (Fc Tag) SDS-PAGE
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