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Product Name
SFTPA1 Polyclonal Antibody
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Description
Polyclonal antibody to SFTPA1
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Tested applications
WB
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Species reactivity
Human, Mouse
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Alternative names
SFTPA1 antibody; COLEC4 antibody; PSAP antibody; PSP-A antibody; PSPA antibody; SFTP1 antibody; SFTPA1B antibody; SP-A antibody; SP-A1 antibody; SPA antibody; SPA1 antibody; surfactant protein A1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human SFTPA1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - SFTPA1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SFTPA1 antibody at 1:200 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 30s.
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Background
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity).; (Microbial infection) Recognition of M.tuberculosis by dendritic cells may occur partially via this molecule. Can recognize, bind, and opsonize pathogens to enhance their elimination by alveolar macrophages.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"