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Product Name
SFRS6 antibody
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Description
SFRS6 Rabbit Polyclonal antibody. Positive WB detected in rat kidney tissue, HeLa cells. Observed molecular weight by Western-blot: 55 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
B52 antibody; FLJ08061 antibody; Pre mRNA splicing factor SRP55 antibody; SFRS6 antibody; SRP55 antibody; SRSF6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SFRS6 recombinant protein (Accession Number: NM_006275). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
rat kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:115151(SFRS6 Antibody) at dilution of 1:600
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Background
SR proteins have a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors [PMID:7556075]. SRFS6 has a pivotal role in the TF exon 5 definition, an event essential for flTF biosynthesis. Besides, up- or down regulation of SRSF6 alters the splicing of several tumor suppressors and oncogenes to generate the oncogenic isoforms and reduce the tumor suppressive isoforms [PMID:23132731].
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"