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Product Name
SFRS5 antibody
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Description
SFRS5 Rabbit Polyclonal antibody. Positive WB detected in A549 cells.
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Delayed early protein HRS antibody; HRS antibody; Pre mRNA splicing factor SRP40 antibody; SFRS5 antibody; SRP40 antibody; SRSF5 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SFRS5 recombinant protein (Accession Number: NM_001039465). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:115150(SFRS5 Antibody) at dilution of 1:300
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Background
SR proteins own a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors [PMID:7556075]. The binding of SR proteins to pre-mRNA appears to be one of the earliest steps in spliceosome assembly, enhancing the binding of U1 snRNP to the 5' splice site to form a commitment complex [PMID:1577277 ]. Alternative splicing has a major role in the regulation of gene expression. SFRS5 belongs to the serine/arginine (SR) protein family of regulators of alternative pre-mRNA splicing [PMID:9244433].
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"