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Product Name
SETD6 antibody
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Description
SETD6 Rabbit Polyclonal antibody. Positive WB detected in RAW 264.7 cells. Observed molecular weight by Western-blot: 53 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ21148 antibody; SET domain containing 6 antibody; SETD6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SETD6 recombinant protein (Accession Number: NM_001160305). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with Catalog No:115223(SETD6 Antibody) at dilution of 1:600
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Background
SETD6 also named as SET domain containing 6 is a 473 amino-acid protein, which localizes in the Nucleus. The molecular weight of SETD6 is 53kDa. SETD6 consists of 1 SET domain and belongs to the class V-like SAM-binding methyltransferase superfamily. SETD6 as a protein-lysine N-methyltransferase that specifically monomethylates at Lysine 310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"