Human PPP3CA (His Tag) recombinant protein

Cat.#: 500232

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Product Information

  • Product Name
    Human PPP3CA (His Tag) recombinant protein
  • Documents
  • Description
    Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
  • Protein name
    Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
  • Protein short names
    PP2B ALPHA 1; CNA; 2900074D19RIK; CALN; PROTEIN PHOSPHATASE 3 (FORMERLY 2B); CNA1; CATALYTIC SUBUNIT; CALCINEURIN A ALPHA; 900074D19RIK; MGC106804; PP2BA ALPHA; AI841391; CAM-PRP CATALYTIC SUBUNIT; CN; ALPHA ISOFORM; CALNA1; CCN1; PPP2B; CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT ALPHA ISOFORM; PROTEIN PHOSPHATASE 2B; SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT ALPHA ISOFORM; CALNA; AW413465
  • Uniprot ID
    Q08209
  • Gene Name
    PPP3CA; CALNA; CNA
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PPP3CA (Q08209-1) (Ser2-Gln521) was fused with a polyhistide tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human PPP3CA consists of 538 amino acids and has a calculated molecular mass of 60.8 kDa. The recombinant protein migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 94 % as determined by SDS-PAGE
  • Activity
    Using the Octet RED System, the affinity constant (Kd) of human PPPP3CA-His (Cat:500232) bound to Human PPIA-His (Cat:501254) was 0.9 nM.
  • Validations

    Human PPP3CA / Protein phosphatase 2B Protein (His Tag) SDS-PAGE

    Human PPP3CA / Protein phosphatase 2B Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"