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Product Name
SERBP1 Polyclonal Antibody
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Description
Polyclonal antibody to SERBP1
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
SERBP1 antibody; CGI-55 antibody; CHD3IP antibody; HABP4L antibody; PAI-RBP1 antibody; PAIRBP1 antibody; SERPINE1 mRNA binding protein 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human SERBP1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - SERBP1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SERBP1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
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Background
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"