SEPT8 antibody

Cat.#: 115122

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Product Information

  • Product Name
    SEPT8 antibody
  • Documents
  • Description
    SEPT8 Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in K-562 cells, HeLa cells, mouse brain tissue, mouse testis tissue, rat brain tissue. Positive IHC detected in human gliomas tissue, human heart tissue. Observed molecular weight by Western-blot: 50-56 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    KIAA0202 antibody; SEP2 antibody; SEPT8 antibody; septin 8 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SEPT8 recombinant protein (Accession Number: BC001329). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:115122(SEPT8 antibody) at dilution of 1:1000

    K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:115122(SEPT8 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:115122(SEPT8 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:115122(SEPT8 antibody) at dilution of 1:50 (under 10x lens)

    IP Result of anti-SEPT8 (IP:Catalog No:115122, 3ug; Detection:Catalog No:115122 1:1000) with HeLa cells lysate 2000ug.

    IP Result of anti-SEPT8 (IP:Catalog No:115122, 3ug; Detection:Catalog No:115122 1:1000) with HeLa cells lysate 2000ug.

  • Background
    SEPT8, also named as KIAA0202, is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking. It may play a role in platelet secretion. SEPT8 is about 50-58 kDa in WB detection.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"