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Product Name
Secretogranin II/Chromogranin C antibody
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Description
Secretogranin II/Chromogranin C Rabbit Polyclonal antibody. Positive IHC detected in human cerebellum tissue, human brain tissue, human pancreas tissue, human small intestine tissue. Positive WB detected in SH-SY5Y cells, Y79 cells. Observed molecular weight by Western-blot: 66 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CHGC antibody; Chromogranin C antibody; SCG2 antibody; Secretogranin 2 antibody; Secretogranin II antibody; SgII antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Secretogranin II/Chromogranin C recombinant protein (Accession Number: NM_003469). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:115095(SCG2 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human cerebellum tissue slide using Catalog No:115095(SCG2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human cerebellum tissue slide using Catalog No:115095(SCG2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
SCG2, also known as secretogranin II or Chromogranin C, is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is widely distributed in nervous and endocrine tissues, and abundant in neuroendocrine granules. In the brain secretogranin II is almost completely processed to secretoneurin, a peptide involved in neurite outgrowth, neuroprotection and neuronal plasticity.
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