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Product Name
SDPR Polyclonal Antibody
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Description
Polyclonal antibody to SDPR
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Tested applications
WB, IHC, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
CAVIN2 antibody; PS-p68 antibody; SDPR antibody; SDR antibody; cavin-2 antibody; caveolae associated protein 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human SDPR
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:2000
IHC 1:20 - 1:200
FC 1:20 - 1:50 -
Validations
Western blot - SDPR Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SDPR antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"