SCNN1A Polyclonal Antibody

Cat.#: 164546

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Product Information

  • Product Name
    SCNN1A Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to SCNN1A
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    SCNN1A antibody; BESC2 antibody; ENaCa antibody; ENaCalpha antibody; SCNEA antibody; SCNN1 antibody; sodium channel epithelial 1 alpha subunit antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A (NP_001029.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:200 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - SCNN1A Polyclonal Antibody

    Western blot - SCNN1A Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using SCNN1A antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 90s.

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence analysis of human lung cancer cells using SCNN1A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence analysis of rat lung cells using SCNN1A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence analysis of mouse kidney cells using SCNN1A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence analysis of human lung cancer cells using SCNN1A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence - SCNN1A Polyclonal Antibody

    Immunofluorescence analysis of rat lung cells using SCNN1A antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

  • Background
    Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"