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  • SCN8A Polyclonal Antibody

SCN8A Polyclonal Antibody

Cat.#: 160212

Special Price 174.2 USD

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Product Information

  • Product Name
    SCN8A Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to SCN8A
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    SCN8A antibody; BFIS5 antibody; CERIII antibody; CIAT antibody; EIEE13 antibody; MED antibody; NaCh6 antibody; Nav1.6 antibody; PN4 antibody; sodium channel protein type 8 subunit alpha antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1350-1440 of human SCN8A (NP_055006.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:200 - 1:1000
  • Validations

    Western blot - SCN8A Polyclonal Antibody

    Western blot - SCN8A Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using SCN8A antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"