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Product Name
Human Sclerostin/SOST (His Tag) recombinant protein
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Description
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
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Protein name
Sclerostin
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Protein short names
SCLEROSTIN; 5430411E23RIK; RP23-398F7.2; SOST; SCLEROSTEOSIS; VBCH; SOST1; CDD
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Uniprot ID
Q9BQB4
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Gene Name
SOST; UNQ2976/PRO7455/PRO7476
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human SOST (NP_079513.1) (Gln 24-Tyr 213) was fused with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SOST is a monomeric protein consisting of 197 amino acids and predicts a molecular mass of 22.5 kDa. As a result of glycosylation, the apparent molecular mass of rhSOST is approximately 28 kDa in SDS-PAGE under reducing conditions..
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human Sclerostin / SOST Protein (His Tag) SDS-PAGE
Related Products / Services
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