Human SOST/UNQ2976/PRO7455/PRO7476 (His tag) recombinant protein

Cat.#: 518458

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Product Information

  • Product Name
    Human SOST/UNQ2976/PRO7455/PRO7476 (His tag) recombinant protein
  • Documents
  • Description
    Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
  • Protein name
    sclerostin(SOST)
  • Protein short names
    UNQ2976; PRO7455; PRO7476
  • Uniprot ID
    Q9BQB4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SOST/UNQ2976/PRO7455/PRO7476 Gln24-Tyr213 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SOST/UNQ2976/PRO7455/PRO7476 (His tag) recombinant protein

    Human SOST/UNQ2976/PRO7455/PRO7476 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"