SCARA5 antibody

SCARA5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

SCARA5 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 43kd

ELISA, WB

Human, Mouse; other species not tested.

FLJ23907 antibody; NET33 antibody; SCARA5 antibody; Scavenger receptor hlg antibody; Tesr antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_173833). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

SCARA5 belongs to the SCARA5 family. It is a ferritin receptor that mediates non-transferrin-dependent delivery of iron. SCARA5 mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. SCARA5 binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). This antibody can recognize isoform 1,2 and 3 of SCARA5.