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Product Name
SBDS antibody
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Description
SBDS Rabbit Polyclonal antibody. Positive IHC detected in human pancreas tissue. Positive WB detected in HL-60 cells, SH-SY5Y cells. Positive IP detected in HL-60 cells. Observed molecular weight by Western-blot: 29 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CGI 97 antibody; FLJ10917 antibody; SBDS antibody; SDS antibody; SWDS antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SBDS recombinant protein (Accession Number: NM_016038). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
HL-60 cells were subjected to SDS PAGE followed by western blot with Catalog No:114979(SBDS antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:114979(SBDS antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:114979(SBDS antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-SBDS (IP:Catalog No:114979, 4ug; Detection:Catalog No:114979 1:300) with HL-60 cells lysate 3040ug.
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Background
Shwachman-Bodian-Diamond syndrome (SBDS) is a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The protein may function in RNA metabolism. Mutations within its gene are associated with Shwachman-Bodian-Diamond syndrome.This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. This antibody is a rabbit polyclonal antibody raised against a full-length human SBDS protein, recognizes specifically the 29kd SBDS protein.
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