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  • Sarconesin II peptide

Sarconesin II peptide

For research use only. We do not sell to patients.

Cat.#: 318770

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Optional Service: TFA RemovalWhat's this?

Special Price 112.5 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    Sarconesin II peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    H-VALTGLTVAEYFR-OH
  • Three letter code
    H-Val-Ala-Leu-Thr-Gly-Leu-Thr-Val-Ala-Glu-Tyr-Phe-Arg-OH
  • Length (aa)
    13
  • Peptide Purity (HPLC)
    95.2
  • Molecular Formula
    C67H106N16O19
  • Molecular Weight
    1439.65
  • Source
    Synthetic
  • Additional Information
    Sarconesin II is a new antimicrobial peptides isolated from Sarconesiopsis magellanica excretions and secretions. Sarconesin II was documented as a conserved domain of the ATP synthase protein belonging to the Fli-1 superfamily. A BLAST search for Calliphoridae multiple sequence alignment revealed sarconesin II’s 100% matching identity with the mitochondrial ATP synthase subunit beta, appearing as a putative conserved domain of the Fli-1 superfamily: flagellar biosynthesis/type III secretory pathway ATPase (Accession: cl25576). Sarconesin II and the conserved domain also appeared in other organisms, such as Homo sapiens (Sequence ID: gi|179279|AAA51808.1), Drosophila melanogaster (gi|442614522|NP_001259081.1) and Mus musculus (gi|31980648|NP_058054.2). Sarconesin II is predicted to have a typical alpha-helix structure. Sarconesin II induced alterations in E. coli cell morphology. Sarconesin II had good activity against Gram-negative and Gram-positive bacteria, including E. coli K12 MG1655.
  • Storage Guidelines
    Ideally Sarconesin II peptide should be stored in a freezer at or below -9C. Sarconesin II peptide should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Du00edaz-Roa A, Espinoza-Culupu00fa A, Torres-Garcu00eda O, et al. Sarconesin II, a New Antimicrobial Peptide Isolated from Sarconesiopsis magellanica Excretions and Secretions. Molecules. 2019;24(11)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Property

  • Analysed Sequence:H-VALTGLTVAEYFR-OH
  • Chemical Formula:C67H106N16O19
  • Sequence length:13
  • Extinction coefficient:1280 M-1cm-1
  • GRAVY:0.87
  • Mw average:1439.65
  • Theoretical pI:7
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"