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SAR1B antibody

Cat.#: 115067

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Special Price 239.0 USD

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Product Information

  • Product Name
    SAR1B antibody
  • Documents
  • Description
    SAR1B Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, mouse brain tissue, mouse skeletal muscle tissue, mouse small intestine tissue, RAW264.7 cells. Positive IHC detected in human liver tissue, human skeletal muscle tissue, human small intestine tissue. Observed molecular weight by Western-blot: 25-27kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ANDD antibody; CMRD antibody; GTBPB antibody; GTP binding protein B antibody; GTP binding protein SAR1b antibody; SAR1 homolog B (S. cerevisiae) antibody; SAR1B antibody; SARA2 antibody; SARB antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_016103). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:115067(SAR1B antibody) at dilution of 1:1000

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:115067(SAR1B antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human liver using Catalog No:115067(SAR1B antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:115067(SAR1B antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:115067(SAR1B antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human liver using Catalog No:115067(SAR1B antibody) at dilution of 1:50 (under 40x lens)

  • Background
    SAR1B, also named as SARA2, SARB and GTBPB, belongs to the small GTPase superfamily and SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus. SAR1B is activated by the guanine nucleotide exchange factor PREB. It is involved in the selection of the protein cargo and the assembly of the COPII coat complex. The antibody is specific to SAR1B.
  • References
    • Fryer LG, Jones B, Duncan EJ. The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis. The Journal of biological chemistry. 289(7):4244-61. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"