-
Product Name
S1PR5/EDG8 antibody
- Documents
-
Description
S1PR5/EDG8 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, HEK-293 cells, HeLa cells, Jurkat cells, K-562 cells. Observed molecular weight by Western-blot: 50-55 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
Edg 8 antibody; EDG8 antibody; S1P receptor 5 antibody; S1P receptor Edg 8 antibody; S1P5 antibody; S1PR5 antibody; SPPR 1 antibody; SPPR 2 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of S1PR5/EDG8 recombinant protein (Accession Number: NM_030760). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115035(S1PR5 Antibody) at dilution of 1:600
-
Background
Sphingosine 1-phosphate (S1P) is a biologically active lysophospholipid that elicits diverse physiological effect on most types of cells and tissues via five G protein-coupled receptors, S1PR1 to S1PR5. S1PRs differ in their tissue expression and cell lineage: S1PR1-3 are expressed throughout the immune, central nervous system (CNS), and cardiovascular system; S1PR4 is primarily expressed in lymphoid tissue; and S1PR5 is a predominant receptor in CNS white matter, spleen and natural killer cells (PMID: 21707490). S1PR5 (also known as EDG8) has been involved in the trafficking of NK cells and monocytes (PMID: 21911833; 23519784).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"