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Product Name
RRBP1 antibody
- Documents
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Description
RRBP1 Rabbit Polyclonal antibody. Positive IF detected in NIH/3T3 cells. Positive IHC detected in human lung cancer tissue, human pancreas tissue. Positive WB detected in mouse pancreas tissue, NIH/3T3 cells. Observed molecular weight by Western-blot: 109 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
DKFZp586A1420 antibody; ES/130 antibody; ES/130 related protein antibody; ES130 antibody; FLJ36146 antibody; hES antibody; KIAA1398 antibody; Ribosome binding protein 1 antibody; Ribosome receptor protein antibody; RRBP1 antibody; RRp antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RRBP1 recombinant protein (Accession Number: BC128577). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:114922(RRBP1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of NIH/3T3 cells using Catalog No:114922(RRBP1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Ribosome-binding protein 1 (RRBP1) is an endoplasmic reticulum membrane protein. It is a 1410 amino acid protein composed of a hydrophobic NH2-terminus that includes a transmembrane domain, a highly conserved tandem repeat (ribosome-binding domain), and an acidic coiled-coil COOH-terminal domain. RRBP1 acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. It is also involved in early cardiac morphogenesis. (PMID: 22709790; 8812507; 7686155)
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