RND3 antibody

RND3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RND3 Mouse Monoclonal antibody. Positive WB detected in fetal human brain tissue. Observed molecular weight by Western-blot: 29 kDa

ELISA, WB

Human, Pig; other species not tested.

ARHE antibody; memB antibody; Protein MemB antibody; Rho family GTPase 3 antibody; Rho8 antibody; RhoE antibody; RND3 antibody

Mouse IgG2b

This antibody was obtained by immunization of RND3 recombinant protein (Accession Number: NM_005168). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.