RNASEH2B antibody

RNASEH2B antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RNASEH2B Rabbit Polyclonal antibody. Positive WB detected in mouse thymus tissue, HeLa cells, MCF7 cells, mouse lung tissue. Observed molecular weight by Western-blot: 35kd

ELISA, WB

human, mouse, rat; other species not tested.

RNASEH2B antibody; ribonuclease H2 antibody; subunit B antibody; FLJ11712 antibody; Ribonuclease H2 subunit B antibody; Ribonuclease HI subunit B antibody

Rabbit IgG

This antibody was obtained by immunization of RNASEH2B recombinant protein (Accession Number: BC036744). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Ribonuclease H2 is the major nuclear enzyme degrading cellular RNA/DNA hybrids in eukaryotes and the sole nuclease known to be able to hydrolyze ribonucleotides misincorporated during genomic replication. RNASEH2B and RNASEH2C are the non-catalytic subunits of RNase H2 complex. Defects in RNASEH2B are a cause of Aicardi-Goutieres syndrome type 2 (AGS2), a genetically heterogeneous disease with clinical features as thrombocytopenia, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process.