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Product Name
RIMBP2 antibody
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Description
RIMBP2 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue. Positive WB detected in mouse kidney tissue, mouse brain tissue. Observed molecular weight by Western-blot: 40-50 kDa, 120-130 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
KIAA0318 antibody; RBP2 antibody; RIM BP2 antibody; RIMBP2 antibody; RIMS binding protein 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RIMBP2 recombinant protein (Accession Number: NM_001351233). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:114704(RIMBP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:114704(RIMBP2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker.
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