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Product Name
RHOD Polyclonal Antibody
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Description
Polyclonal antibody to RHOD
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Tested applications
WB, IF
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Species reactivity
Human
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Alternative names
RHOD antibody; ARHD antibody; RHOHP1 antibody; RHOM antibody; Rho antibody; ras homolog family member D antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human RHOD (NP_055393.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:100 -
Validations
Immunofluorescence - RHOD Polyclonal Antibody
Immunofluorescence analysis of MCF-7 cells using RHOD antibody . Blue: DAPI for nuclear staining.
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Background
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"