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Product Name
RGS9 antibody
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Description
RGS9 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 58kd,70-75kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
RGS9 antibody; PERRS antibody; RGS9L antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of RGS9 recombinant protein (Accession Number: BC022504). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114650(RGS9 antibody) at dilution of 1:500
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Background
RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).
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