Human Renin (His Tag) recombinant protein

Cat.#: 501755

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Product Information

  • Product Name
    Human Renin (His Tag) recombinant protein
  • Documents
  • Description
    Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
  • Protein name
    Renin
  • Protein short names
    REN-A; RN-1; FLJ10761; REN; REN1D; RENIN; REN-1; RNR; REN1C; HNFJ2; D19352
  • Uniprot ID
    P00797
  • Gene Name
    REN
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human Renin (NP_000528.1) precursor (Met 1-Arg 406) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human Renin is a monomeric protein after cleavage of the signal peptide. The pro form consists of 394 amino acids and predictes a molecular mass of 43.7 kDa. In SDS-PAGE under reducing conditions, it migrates with the apparent molecular mass of 50 kDa due to glycosylation.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized human RENIN-His (Cat: 501755) at 10 μg/ml (100 μl/well) can bind biotinylated human AGT-His (Cat: 501652) with a linear range of 0.156-5.0 μg/ml.
  • Validations

    Human Renin Protein (His Tag) SDS-PAGE

    Human Renin Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"