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Product Name
Human REG3G (His Tag) recombinant protein
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Description
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
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Protein name
Regenerating islet-derived protein 3-gamma
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Protein short names
UNQ429; AI449515; MGC118998; MGC118999; REGIII; PAP-1B; PAP1B; LPPM429; REG-III; PAP IB; UNQ429/PRO162; REG3G; PAPIB; MGC119001
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Uniprot ID
Q6UW15
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Gene Name
REG3G; PAP1B; UNQ429/PRO162
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human REG3G (NP_001008388.1) (Met 1-Asp 175) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human REG3G consists of 160 amino acids and migrates as an approximately 18 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human REG3G / PAP1B Protein (His Tag) SDS-PAGE
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