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Product Name
Recombinant 2019-nCoV 3C-like Proteinase (N-6His)
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Description
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
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Protein short names
M Proteinase; 3CL Proteinase
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Uniprot ID
YP_009725301.1
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
6His tag was fused to N-terminus of 2019-nCoV 3C-like Proteinase
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Protein Species
Severe acute respiratory syndrome coronavirus 2
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Molecular weight
36.1kDa
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Purity
>95%
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Activity
Measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic).
The specific activity is >13000pmol/min/mg. -
Validations
Recombinant 2019-nCoV 3C-like Proteinase (N-6His)
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"