RCOR2 antibody

RCOR2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RCOR2 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HEK-293 cells. Observed molecular weight by Western-blot: 58

ELISA, WB

Human, Mouse; other species not tested.

RCOR2 antibody; REST corepressor 2 antibody

Rabbit IgG

This antibody was obtained by immunization of RCOR2 recombinant protein (Accession Number: NM_173587). Purification method: Antigen Affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

In mammals, the CoREST (corepressor for element-1-silencing transcription factor) complex is a chromatin-modifying structure that, through interactions with NRSF (neuron restrictive silencer factor), regulates neuronal gene expression and neuronal cell fate. RCOR2 (REST corepressor 2) and RCOR3 (REST corepressor 3) are nuclear proteins that each contain one ELM2 domain and two SANT domains. RCOR2 and RCOR3, both members of the CoREST family, are thought to function as components of the CoREST complex, possibly playing a role in the transcriptional repression of neuronal genes. Additionally, RCOR2 and RCOR3, in conjunction with CoREST, can form immunocomplexes with a variety of histone-modifying genes, including G9a and HDAC1. Via these protein complexes, RCOR2 and RCOR3 can further regulate transcription by controlling the methylation and demethylation of target genes during early development.