RBBP9 antibody

RBBP9 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RBBP9 Mouse Monoclonal antibody. Positive IHC detected in human pancreas tissue. Positive IF detected in Hela cells. Positive WB detected in A549 cells. Observed molecular weight by Western-blot: 22kD

ELISA, WB, IF, IHC

Human; other species not tested.

Mouse IgG2b

This antibody was obtained by immunization of RBBP9 recombinant protein (Accession Number: NM_006606). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

RBBP9, also named as BOG, RBBP10, RBBP-9, RBBP-10 and Protein BOG, belongs to the RBBP9 family. It may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-β1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. RBBP9 is a tumor-associated serine hydrolase activity required for pancreatic neoplasia. It mediates suppression of TGF-β signaling is required for E-cadherin expression as loss of the serine hydrolase activity leads to a reduction in E-cadherin levels and a concomitant decrease in the integrity of tumor cell–cell junctions..RBBP9 protein levels were equivalent in paired primary tumor and nonneoplastic specimens(PMID:20080647)