Rat LILRA5 (Fc Tag) recombinant protein

Rat LILRA5 (Fc Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

Protein Lilra5

LILRB7; CD85 ANTIGEN-LIKE FAMILY MEMBER F; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR; LIR-9; ILT-11; MEMBER 7; ILT11; XXBAC-BCX403H19.2; CD85; LIR9; SUBFAMILY B (WITH TM AND ITIM DOMAINS); LEUKOCYTE IG-LIKE RECEPTOR 9; CD85F; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 5; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 5 SOLUBLE; GM4878; E030017K20; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR 9; LILRC1; IMMUNOGLOBULIN-LIKE TRANSCRIPT 11 PROTEIN; EG232801

D4A6Y0

Lilra5

Human Cells

A DNA sequence encoding the rat LILRA5 (D4A6Y0) (Met1-Asn248) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Rat

The recombinant rat LILRA5/Fc is a disulfide-linked homodimer. The reduced monomer comprises 473 amino acids and has a predicted molecular mass of 52.8 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.

> 90 % as determined by SDS-PAGE