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Product Name
RASGRP2 antibody
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Description
RASGRP2 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, mouse liver tissue, mouse lung tissue. Observed molecular weight by Western-blot: 48kd
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CALDAG GEFI antibody; Cdc25 like protein antibody; CDC25L antibody; F25B3.3 kinase like protein antibody; hCDC25L antibody; MCG7 antibody; RAS guanyl releasing protein 2 antibody; RASGRP2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_153819). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:114478(RASGRP2 antibody) at dilution of 1:300
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Background
RASGRP2, also named as CDC25L and MCG7, belongs to the RASGRP family. It functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. RASGRP2 may also activate other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. RASGRO2 functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. It may function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway. The antibody recognizes the C-term of RASGRP2.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"