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RARG antibody

Cat.#: 114469

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Product Information

  • Product Name
    RARG antibody
  • Documents
  • Description
    RARG Rabbit Polyclonal antibody. Positive IP detected in MCF-7 cells. Positive WB detected in HeLa cells, MCF-7 cells. Observed molecular weight by Western-blot: 50 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    NR1B3 antibody; RAR gamma antibody; RARC antibody; RARG antibody; Retinoic acid receptor gamma antibody; retinoic acid receptor antibody; gamma antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of RARG recombinant protein (Accession Number: BC019098). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114469(RARG antibody) at dilution of 1:400

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114469(RARG antibody) at dilution of 1:400

    IP Result of anti-RARG (IP:Catalog No:114469, 4ug; Detection:Catalog No:114469 1:300) with MCF-7 cells lysate 1120ug.

    IP Result of anti-RARG (IP:Catalog No:114469, 4ug; Detection:Catalog No:114469 1:300) with MCF-7 cells lysate 1120ug.

  • Background
    Retinoic acid receptors (RARs) are nuclear hormone receptors that act as ligand-dependent transcriptional regulators. In their liganded state, RARs activate transcription, whereas in their nonliganded form, they repress transcription of their target genes. RARs have numerous target genes, which have retinoic response elements in their promoter regions [PMID:17574023]. RARG is a member of the retinoid acid receptor (RAR) family, along with RARA, which is known to be involved PML/RARA fusion of acute promyelocytic leukemia, and RARB. and rearrangement that conferred to leukemic cells acute promyelocytic leukemia–like morphologic and immunophenotypic features [PMID:20935257].
  • References
    • Volle DH, Decourteix M, Garo E. The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice. The Journal of clinical investigation. 119(12):3752-64. 2009.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"