-
Product Name
RAP2B antibody
- Documents
-
Description
RAP2B Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, HEK-293 cells. Observed molecular weight by Western-blot: 19-22 kDa
-
Tested applications
ELISA, WB
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
RAP2B antibody; Ras related protein Rap 2b antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of RAP2B recombinant protein (Accession Number: NM_002886). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114550(RAP2B antibody) at dilution of 1:500
-
Background
RAP2B belongs to a family of RAS-related genes. It share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. Rap2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway.
-
References
- Li Y, Martin BR, Cravatt BF, Hofmann SL. DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells. The Journal of biological chemistry. 287(1):523-30. 2012.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"