RABEPK antibody

RABEPK antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RABEPK Rabbit Polyclonal antibody. Positive IHC detected in human ovary tumor. Positive WB detected in HeLa cells, K-562 cells. Observed molecular weight by Western-blot: 44kd

ELISA, WB, IHC

human, mouse, rat; other species not tested.

RABEPK antibody; p40 antibody; RAB9P40 antibody; 40 kDa Rab9 effector protein antibody; DKFZp686P1077 antibody

Rabbit IgG

This antibody was obtained by immunization of RABEPK recombinant protein (Accession Number: NM_001174152). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.