RAB27A antibody

RAB27A antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

RAB27A Mouse Monoclonal antibody. Positive IHC detected in human skeletal muscle tissue. Positive WB detected in K562 cells, K-562 cells. Observed molecular weight by Western-blot: 27 kDa

ELISA, WB, IHC

Human; other species not tested.

GS2 antibody; GTP binding protein Ram antibody; HsT18676 antibody; Rab 27 antibody; RAB27 antibody; RAB27A antibody; RAM antibody; Ras related protein Rab 27A antibody

Mouse IgG1

This antibody was obtained by immunization of RAB27A recombinant protein (Accession Number: XM_011521855). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.