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Product Name
Mouse CD52 / CDW52 (Fc Tag) recombinant protein
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Description
CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
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Protein name
Putative uncharacterized protein
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Protein short names
LYMPHOCYTE DIFFERENTIATION ANTIGEN B7; HUMAN EPIDIDYMIS-SPECIFIC PROTEIN 5; CLS1; RP23-314D24.5; EPIDIDYMAL SECRETORY PROTEIN E5; CDW52 ANTIGEN (CAMPATH-1 ANTIGEN); MB7; B7; AI463198; CDW52; B7-AG; CAMBRIDGE PATHOLOGY 1 ANTIGEN; CD52 ANTIGEN (CAMPATH-1 ANTIGEN); CAMPATH-1 ANTIGEN; HE5; CAMPATH-1
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Uniprot ID
Q64389
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Gene Name
Cd52
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Cd52 (NP_038734.1) (Met1-Lys46) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Cd52 consists 261 amino acids and predicts a molecular mass of 29 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse Cd52 / CDw52 Protein (Fc Tag) SDS-PAGE
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