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Product Name
Cynomolgus LAMP2/CD107b (His Tag) recombinant protein
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Description
LAMP2 (Lysosomal-associated membrane protein 2), also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. In human, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy.
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Protein name
Putative uncharacterized protein
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Protein short names
LAMP-2; LAMPB; RP23-193O17.2; LAMPII; CD107B; LAMP-2A; LGP-B; LAMP2; LAMP-2B; LGP110; LAMP-2C; MAC3
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Uniprot ID
G7Q3L7
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Gene Name
EGM_19144
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the cynomolgus LAMP2 (G7Q3L7) (Leu29-Phe376) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Cynomolgus
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Molecular weight
The recombinant cynomolgus LAMP2 comprises 359 amino acids and has a calculated molecular mass of 39.8 KDa. The apparent molecular mass of it is approximately 64-68 KDa respectively in SDS-PAGE.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Cynomolgus LAMP2 Protein (His Tag) SDS-PAGE
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